As you may be already aware of that there is big change for Internet Explorer support which had been already announced by Microsoft. Please read Microsoft page

Support for older versions of Internet Explorer ended on January 12th, 2016.

SAP WebCUIF cannot support browser versions that vendors no more support themselves. The corresponding SAP Note 1746385 - Main WEBCUIF Browser Support Notehas been updated. Following is an abstract from this note, but you should always check and follow SAP Note 1746385 which will be updated timely.

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WEBCUIF has to support different browser versions, as those come and go.

●SAP WebCUIF cannot support browser versions that vendors no more support themselves.

Along that line, SAP recommendations follow those of Microsoft: on January 12th 2016, Microsoft recommends for security purposes that the latest version of IE supported by each platform to be run. From http://blogs.msdn.com/b/ie/archive/2014/08/07/stay-up-to-date-with-internet-explorer.aspx :

Beginning January 12, 2016, the following operating systems and browser version combinations will be supported:

      Windows Platform                  Internet Explorer Version

      Windows Vista SP2                 Internet Explorer 9

      Windows Server 2008 SP2      Internet Explorer 9

      Windows 7 SP1                      Internet Explorer 11

      Windows Server 2008 R2 SP1  Internet Explorer 11

      Windows 8.1                          Internet Explorer 11

      Windows Server 2012             Internet Explorer 10 

      Windows Server 2012 R2        Internet Explorer 11

After January 12, 2016, only the most recent version of Internet Explorer available for a supported operating system will receive technical support and security updates. For example, customers using Internet Explorer 8, Internet Explorer 9, or Internet Explorer 10 on Windows 7 SP1 should migrate to Internet Explorer 11 to continue receiving security updates and technical support."

●As soon as a vendor releases a new browser version, SAP WebCUIF commits to fix any issue as soon as possible, via Notes when possible, and SPs for complete solutions.

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Additionally, Please also check following blog about how to find if Safari and Google Chrome are supported or not by CRM Interaction Center.

How to find which Web Browsers are supported by SAP CRM Interaction Center?

Best Regards,

Bruce